In the book, Arjun was Indian while Sean was presumably Caucasian, and in the episode, it is the other way around.
Alex's parents are in London instead of France. He also arrives at night instead of during the day, and Colin is the only one to pick him up. In the episode, he has to wait all night for them to show up. In the book, Colin and Marta pick Alex up from the bus station soon after he arrives. In the book, Hannah told him that she brought the skin she wore from home then attacked him. Alex looks at her concerned, unsure of what she is about to do. As the episode ends, just after he learns the truth about Hannah, she enters the room. Alex's fate is slightly more ambiguous. Instead, Alex buries the wolf skins, and when the full moon is at its' peak, the skins blow up, curing Uncle Colin and Aunt Marta from the curse. 
Alex and Hannah do not wear the wolf skins as an attempt to make sure Uncle Colin and Aunt Marta don't get them to transform. 
In the episode, the skins are full-body werewolf costumes.
In the book, the wolf skins are described as looking like capes of dark fur. The episode does not take place around Halloween. Alex's last name is Blackwell, instead of Hunter. Terra Vnesa as Hannah Stoneman (as Terra Vanessa Kowalyk).
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